By:
Nickolaos D. Skouras, PhD.
The Metabolic Syndrome, or
“Syndrome-X”, as it is often called is the combination of Obesity,
Hypercholestroelimia, and Hypertension, they are all
linked together by an underlying resistance to Insulin. This condition is often associated with
excess insulin secretion.
This syndrome was first described by
Reaven in 1998. Unfortunately its
principal component of obesity was not initially
emphasized. So common and so pernicious
are the negative health outcomes of the Metabolic Syndrome that it qualifies as
the number one public problem that is facing several western societies.
Recently the House of Commons Committee has
officially reported that obesity has reached serious levels amongst the
population in the
This staggering statistic is alarming not only for
the abundant health risks faced by an overweight individual, but also for the
enormous and often hidden costs of treating ailments and diseases caused or
exacerbated by obesity. Additionally,
new research indicates that a restricted caloric intake can lead to a longer
life. But a calorie-rich diet isn't
always the single cause of obesity, and the hunger pains associated with diets
that severely limit the quantity of food eaten rarely make these plans successful.
One of the most underrated problems many overweight
people face is the blow the excess weight is to their self-esteem. The overwhelming message our society
reiterates to the overweight person is that he simply "lacks
willpower," and if he would just "buckle down" he could face the
challenge. But many chronically
overweight adults have addressed the issue (often many times in their life)
through a change of diet, exercising, or following one of the thousands of
quick-fix diets and eating plans available to the average British
consumer. Sometimes the struggle is too
great and the success is limited to a few weeks. Or the individual loses all his weight, only
to regain it (and maybe more) back later.
The feeling of failure and shame this causes is traumatic, and people
resign themselves to just being fat.
Many people find themselves temporarily overweight
for a variety of reasons. Perhaps a new
job leaves someone more sedentary than a previous position, a woman who has
just given birth has put on extra weight during pregnancy, or an individual
finds himself responsible for the first time in his life to cook his own food
and he doesn't have the skills necessary to create healthy, balanced
meals. These examples and many other
temporary conditions are often overcome with proper training, a resumption in
regular routines or a boost in activity level.
However, many new clinical studies indicate that there are many
overweight people who have a chronic disease
called obesity. For these people,
willpower and exercise alone are not enough.
Their problem needs to be treated like any other medical problem - a
bodily imbalance that can be corrected in order to assist the individual to
maximize the potential for weight loss.
If the overweight individual approaches obesity as a
medical condition, the shame and helplessness associated with endless dieting
successes and failures can be eliminated.
A sensible program can be developed with a primary
care provider that includes healthy food choices, moderate exercise and
supplementation to address the body's chemical imbalance. Living free of excess weight is enough to
make a person feel great. But the
long-term benefits of weight loss greatly reduce the risk of serious medical
conditions including Insulin Resistance, Diabetes, Cardiovascular disease and
certain forms of Cancer. And that makes
a successful approach to weight loss even more important.
What can be
done to treat obesity?
Many dietary programs, books, groups and drugs are
available for those seeking to lose weight in the United Kingdom. These range from sensible, healthy plans
developed with a primary care provider, to fad diets and "fat
blocking" pills promoted in the latest tabloid magazine. Other supplements labeled as Thermogenics are
sold as metabolic enhancers, aside from just increasing the internal body heat,
they are primarily composed of herbal stimulants. This can only exacerbate the Obesity problem
by possibly causing Heart failure or Stroke.
Until now the only scientific answer to the problem
is a combined program of reduced caloric intake increased daily activity
including exercise and a change in long-term life style conditioning.
Since during
the Evolutionary Origin of the Human Cellular Metabolism the “Citric Acid Cycle
was and still is the Core of Biology.“
Considerable attention has been paid to the development of specific
molecules such as Coenzyme A that are able to reduce Insulin resistance.
Dr. Chris
Newgard and colleagues from Duke University Medical Center published the latest
research paper “Nature Medicine” on March 9th, 2004. Using Obese and Insulin resistant rats in
their studies. The researchers
conclusively demonstrated that significant health benefits could be achieved by
the supplementation of the natural food sources of Coenzyme A (whole animal,
muscle meats, hearts, and livers).
These benefits would not only be for prevention purposes
but also for the treatment and reversal of some very serious disease conditions
such as are being discussed in this paper.
This is accomplished by increasing the endogenous
concentrations of Coenzyme-A and Acetyl Coenzyme A, into ones body. Which
intern results in the “Over-expression”, that acts as caloric partitioning
mechanism thus directing fatty acids to be metabolically broken down, and
recycled in the human cell for energy production and finally oxidized out of
the body.
New
Developments
Coenzyme-A Technologies, Inc., has applied its
innovative proprietary Coenzyme A Modulator Matrix ITM to the creation of a
nutraceutical product that contains a balanced combination of active
nutritional components that support the body's natural management of fat. Coenzyme-ATM, in conjunction with proper diet and exercise, may
produce phenomenal results in fat loss, reversing Insulin Resistance and high
blood Cholesterol, while maintaining energy levels and preventing hunger and
weakness.
Who is
Coenzyme-A Technologies Inc.?
Coenzyme-A Technologies Inc. is the world's first
developer of effective Coenzyme-A and
Acetyl Coenzyme-A products. Coenzyme-A Technologies, Inc. has applied new
technology to the formulation and manufacture of a series of proprietary
products which address nutritional deficiencies that result from the stress of
modern day living, chemical imbalances within the body, and the effects of
aging.
"Coenzyme-ATM" is the first nutraceutical
product to combine nutritional components that can be used by the body to
support its manufacture and utilization of Coenzyme-A (The Master Coenzyme)
with a specific set of substrates that are designed to assist the body in
metabolizing fat.
The benefits
of Coenzyme-ATM include:
·
The Pyruvate component, working to primarily enhance the transport of
glucose into the muscle cells from the blood.
Scientific studies show it increases (glucose extraction) from 150% to
300%.
·
Cardiovascular benefits such as providing an alternative and more
beneficial energy source thus improving the performance of a healthy or
dysfunctional heart.
·
Acetyl L-Carnitine, the acetyl ester of L-Carnitine (a more
biologically active form of Carnitine), is the carrier of fatty acids across mitochondrial
membranes.
·
In the body, Acetyl L-Carnitine modulates cellular concentration of
free Coenzyme-A and Acetyl Coenzyme-A compounds, and is integrally involved in
numerous cellular functions including energy production by exchanging across
sub-cellular membranes. Acetyl
L-Carnitine serves as a pool of acetyl groups to regenerate Acetyl Coenzyme-A
from free Coenzyme-A.
·
Increases energy production in the body within the processes of the
tricarboxylic acid (TCA) and glycolitic cycles.
·
Metabolizes fat and reduces cholesterol and triglycerides by increasing
fat utilization.
·
Stabilizes blood sugar levels, maintaining a healthy balance of
insulin.
·
Synthesizes fatty acids needed for healthy hormonal production.
·
Enhances physical performance, and the overall sense of well being.
Copyright ©
2007 Coenzyme-A Technologies Inc.TM All rights reserved.